TheZEPROJECT Catalogue

Cognitive · Compound profile

Selank

Tuftsin analogue

Anxiolysis without sedation.

GABAEnkephalins
Abstract brand visual representing Selank, a tuftsin analogue

How Selank works

Selank is a synthetic analogue of the immunopeptide tuftsin. It modulates GABAergic transmission and stabilises enkephalin levels by inhibiting their breakdown, producing an anxiolytic effect that does not carry the sedation, tolerance or withdrawal profile of benzodiazepines.

Reported benefits

  • Reduced anxiety and stress reactivity
  • No sedation or dependence profile
  • Improved emotional stability and sleep quality
  • Mild immune-modulating effect

Reported side effects

Effects reported in published trials, case reports or post-market surveillance. Individual response varies; this list is educational and not exhaustive.

  • Drowsiness or flattened affect
  • Nasal irritation intranasally
  • Headache
  • Human data largely limited to Russian clinical practice

Regulatory status & sources

Not FDA approved — research use only

No FDA approval. Selank is a registered anxiolytic in Russia only.

Safety note

Selank is presented here for research and educational purposes only. It is not offered for human consumption and nothing on this page is medical advice or a dosing protocol. Read the full safety and disclaimer page.