How GHK-Cu works
GHK-Cu delivers copper into the dermis and acts as a transcriptional modulator, shifting hundreds of genes toward repair: collagen I and III synthesis up, matrix metalloproteinase-driven breakdown down. The result is remodelling rather than surface hydration.
Reported benefits
- Increased collagen and elastin synthesis
- Improved wound healing and scar quality
- Reduced fine lines and skin laxity
- Antioxidant support in the dermis
Reported side effects
Effects reported in published trials, case reports or post-market surveillance. Individual response varies; this list is educational and not exhaustive.
- Topical stinging, redness or dryness
- Contact irritation at higher concentrations
- Rare copper sensitivity reactions
Regulatory status & sources
Cosmetic / topical ingredient
Not an FDA-approved drug. GHK-Cu is used as a cosmetic ingredient; injectable use is unapproved and research-only.
Safety note
GHK-Cu is presented here for research and educational purposes only. It is not offered for human consumption and nothing on this page is medical advice or a dosing protocol. Read the full safety and disclaimer page.